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Note: This can be used for EMR and resection cancer synoptics, based on the procedure performed.
Procedure
Abdominoperineal resection
Excisional biopsy (polypectomy)
Local (transanal disk) excision
Other
Not specified
Specimen
Anal canal
Anorectal junction
Rectum
Perianal skin
Other
Not specified
Specimen Integrity
Not applicable
Intact
Fragmented
Other
Tumor Site
Anal canal
Perianal region
Anus, not otherwise specified
Unknown
Other
Tumor Size (cm)
Histologic Type
Squamous cell carcinoma
Verrucous carcinoma
Adenocarcinoma
Large cell neuroendocrine carcinoma
Small cell neuroendocrine carcinoma
Mixed adenoneuroendocrine non-neuroendocrine neoplasm
Other histologic type
Histologic Grade
G1: Well differentiated
G2: Moderately differentiated
G3: Poorly differentiated
G4: Undifferentiated
Other
GX: Cannot be assessed
Not applicable
Tumor Extension
No evidence of primary tumor
Carcinoma in situ
Tumor invades lamina propria
Tumor invades muscularis mucosae
Tumor invades submucosa
Tumor invades into but not through anal sphincter muscle
Tumor invades into but not through muscularis propria of rectum
Tumor invades through anal sphincter muscle into perianal or perirectal soft tissue without involvement of adjacent structures
Tumor directly invades adjacent structures
Tumor invades perianal skin
Margins
All margins are uninvolved by invasive carcinoma, intramucosal adenocarcinoma, high-grade dysplasia, and adenoma
One or more margins involved by neoplasia
Proximal Margin
Cannot be assessed
Uninvolved by invasive carcinoma and high-grade intraepithelial neoplasia
Uninvolved by invasive carcinoma
Involved by invasive carcinoma
Involved by high-grade intraepithelial neoplasia
Distal Margin
Cannot be assessed
Uninvolved by invasive carcinoma and high-grade intraepithelial neoplasia
Uninvolved by invasive carcinoma
Involved by invasive carcinoma
Involved by high-grade intraepithelial neoplasia
Radial (Circumferential) Margin
Cannot be assessed
Uninvolved by invasive carcinoma
Involved by invasive carcinoma
Other Margin
Not applicable
Cannot be assessed
Uninvolved by invasive carcinoma
Involved by invasive carcinoma
Treatment Effect
A word about scoring treatment effect
No known presurgical therapy
Present, complete response, score 0
Present, near complete response, score 1
Present, partial response, score 2
Absent, poor or no response, score 3
Cannot be determined
+ Lymphovascular Invasion
Not identified
Present
Cannot be determined
+ Perineural Invasion
Not identified
Present
Cannot be determined
Regional Lymph Nodes
Pathologic Staging (pTNM)
TNM Descriptors (select all that apply)
Not applicable
m
r
y
pT
pTX: Primary tumor not assessed
pT0: No evidence of primary tumor
pTis: High-grade squamous intraepithelial lesion
pT1: Tumor ≤2 cm
pT2: Tumor >2 cm but ≤5 cm
pT3: Tumor >5 cm
pT4: Tumor of any size invading adjacent organ(s)
pN
pNX: Regional lymph nodes cannot be assessed
pN0: No regional lymph node metastasis
pN1a: Metastasis in inguinal, mesorectal, or internal iliac lymph nodes
pN1b: Metastasis in external iliac lymph nodes
pN1c: Metastasis in external iliac with any N1a nodes
pM
pMx: Not applicable
pM1: Distant metastasis
+ Additional Pathologic Findings
None identified
Crohn disease
Condyloma acuminatum
Anal fistula
Dysplasia
Associated rectal carcinoma (Paget disease)
Other
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