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Procedure

Appendectomy Appendectomy and right colectomy Other

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+ Tumor Site

Proximal half of appendix Base of appendix involved by tumor Base of appendix uninvolved by tumor Involvement of base of appendix cannot be assessed Distal half of appendix Diffusely involving appendix Appendix, not otherwise specified Other

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Tumor Size (cm)

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Histologic Type

Adenocarcinoma Mucinous adenocarcinoma Low-grade appendiceal mucinous neoplasm High-grade appendiceal mucinous neoplasm Signet-ring cell carcinoma Goblet cell adenocarcinoma Large cell neuroendocrine carcinoma Small cell neuroendocrine carcinoma Mixed neuroendocrine-non-neuroendocrine neoplasm (Mixed adenoneuroendocrine carcinoma) Medullary carcinoma Adenosquamous carcinoma Undifferentiated carcinoma Other histologic type Carcinoma, type cannot be determined

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Histologic Grade A word about grading mucinous and non-mucinous tumors

×

A word about grading mucinous and non-mucinous tumors

G1: Well differentiated G2: Moderately differentiated G3: Poorly differentiated Other GX: Cannot be assessed Not applicable

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Tumor Extension

No evidence of primary tumor Tumor invades lamina propria or muscularis mucosa Tumor invades submucosa Tumor invades muscularis propria Acellular mucin invades subserosa or mesoappendix but does not extend to the serosal surface Tumor invades through the muscularis propria into the subserosa or mesoappendix but does not extend to the serosal surface Acellular mucin invades the visceral peritoneum (serosa) Tumor invades the visceral peritoneum (serosa) Tumor directly invades adjacent organs Cannot be assessed

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Margins

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Lymphovascular Invasion

Not identified Present Cannot be determined

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Tumor Deposits

Not identified Present Cannot be determined

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+ Perineural Invasion

Not identified Present Cannot be determined

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Regional Lymph Nodes

Check here if any lymph nodes submitted?

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Pathologic Staging (pTNM)

TNM Descriptors (select all that apply)

Not applicable m r y

pT

pTX: Primary tumor cannot be assessed pT0: No evidence of primary tumor pTis: Carcinoma in situ (intramucosal carcinoma; invasion of the lamina propria or extension into but not through the muscularis mucosae) pTis(LAMN): Low-grade appendiceal mucinous neoplasm confined by the muscularis propria. (Acellular mucin or mucinous epithelium may invade into the muscularis propria) pT1: Tumor invades the submucosa (through the muscularis mucosa but not into the muscularis propria) pT2: Tumor invades the muscularis propria pT3: Tumor invades through the muscularis propria into the subserosa or mesoappendix pT4a: Tumor invades through the visceral peritoneum, including the acellular mucin or mucinous epithelium involving the serosa of the appendix or serosa of the mesoappendix pT4b: Tumor directly invades or adheres to adjacent organs or structures

pN

pNX: Regional lymph nodes cannot be assessed pN0: No regional lymph node metastasis pN1a: One regional lymph node is positive pN1b: Two or three regional lymph nodes are positive pN1c: No regional lymph nodes are positive, but there are tumor deposits in the subserosa or mesentery pN2: Four or more regional lymph nodes are positive

pM

pMx: Not applicable pM1a: Intraperitoneal acellular mucin, without identifiable tumor cells in the disseminated peritoneal mucinous deposits# pM1b: Intraperitoneal metastasis only, including peritoneal mucinous deposits containing tumor cells pM1c: Metastasis to sites other than peritoneum

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+ Additional Pathologic Findings

None identified Appendicitis Perforation, not at tumor Ulcerative colitis Crohn disease Diverticulosis Other