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Procedure

Partial cystectomy Total cystectomy Radical cystectomy Radical cystoprostatectomy Anterior exenteration Other Cannot be determined

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Tumor Site

Trigone Right lateral wall Left lateral wall Anterior wall Posterior wall Dome Other Cannot be determined

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Tumor Size (cm)

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Histologic Type

Papillary Urothelial carcinoma, noninvasive Papillary Urothelial carcinoma, invasive Urothelial carcinoma in situ Urothelial carcinoma, invasive Urothelial carcinoma, nested (including large nested) variant Urothelial carcinoma, microcystic variant Urothelial carcinoma, micropapillary variant Urothelial carcinoma, lymphoepithelioma-like variant Urothelial carcinoma, plasmacytoid / signet ring / diffuse variant Urothelial carcinoma, sarcomatoid variant Urothelial carcinoma, giant cell variant Urothelial carcinoma, poorly differentiated variant Urothelial carcinoma, lipid-rich variant Urothelial carcinoma, clear cell variant Urothelial carcinoma with squamous differentiation Urothelial carcinoma with glandular differentiation Urothelial carcinoma with trophoblastic differentiation Urothelial carcinoma with Mϋllerian differentiation Squamous cell carcinoma Verrucous (Squamous cell) carcinoma Squamous cell carcinoma in situ only Adenocarcinoma Adenocarcinoma, enteric Adenocarcinoma, mucinous Adenocarcinoma, mixed Adenocarcinoma in situ only Clear cell carcinoma Endometrioid carcinoma Small cell neuroendocrine carcinoma Large cell neuroendocrine carcinoma Well-differentiated neuroendocrine carcinoma Other histologic type

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+ Associated Epithelial Lesions

None identified Urothelial papilloma Urothelial papilloma, inverted type Papillary urothelial neoplasm, low malignant potential (PUNLMP) Urothelial proliferation of uncertain malignant potential Urothelial dysplasia Cannot be determined

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+ Tumor Configuration

Papillary Solid/nodule Flat Ulcerated Cannot be determined Other

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Tumor Extension

No evidence of primary tumor Noninvasive papillary carcinoma Urothelial carcinoma in situ, “flat tumor” Tumor invades lamina propria (subepithelial connective tissue) Tumor invades superficial muscularis propria (inner half) Tumor invades deep muscularis propria (outer half) Tumor microscopically invades perivesical tissue Tumor macroscopically invades perivesical tissue (extravesical mass) Tumor invades adjacent structures Cannot be assessed

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Margins

Uninvolved by invasive carcinoma and carcinoma in situ/ noninvasive urothelial carcinoma Uninvolved by invasive carcinoma Involved by invasive carcinoma Involved by carcinoma in situ/noninvasive high-grade urothelial carcinoma Involved by noninvasive low-grade urothelial carcinoma/urothelial dysplasia

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Lymphovascular Invasion

Not identified Present Cannot be determined

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Regional lymph nodes

Check here if any lymph nodes submitted?

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Pathologic Staging (pTNM)

Click for information on depth of invasion

TNM Descriptors (select all that apply)

Not applicable m r y

pT Staging diagram

pTX: Primary tumor cannot be assessed pT0: No evidence of primary tumor pTa: Noninvasive papillary carcinoma pTis: Urothelial carcinoma in situ: “flat tumor” pT1: Tumor invades lamina propria (subepithelial connective tissue) pT2: Tumor invades muscularis propria pT2a: Tumor invades superficial muscularis propria (inner half) pT2b: Tumor invades deep muscularis propria (outer half) pT3: Tumor invades perivesical soft tissue pT3a: Tumor invades perivesical soft tissue microscopically pT3b: Tumor invades perivesical soft tissue macroscopically (extravesical mass) pT4: Extravesical tumor directly invades any of the following: prostatic stroma, seminal vesicles, uterus, vagina, pelvic wall, abdominal wall pT4a: Extravesical tumor invades directly into prostatic stroma, seminal vesicles, uterus, or vagina pT4b: Extravesical tumor invades pelvic wall, abdominal wall

pN

pNX: Lymph nodes cannot be assessed pN0: No lymph node metastasis pN1: Single regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac or sacral lymph node) pN2: Multiple regional lymph node metastasis in the true pelvis (perivesical, obturator, internal and external iliac or sacral lymph node metastasis) pN3: Lymph node metastasis to the common iliac lymph nodes

pM

pMx: Not applicable pM1a: Distant metastasis limited to lymph nodes beyond the common iliacs pM1b: Non-lymph node distant metastases

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+ Additional Pathologic Findings (select all that apply)

Urothelial carcinoma in situ Urothelial dysplasia, low-grade Adenocarcinoma of prostate Inflammation/regenerative changes Therapy-related changes Cystitis cystica et glandularis Keratinizing squamous metaplasia Intestinal metaplasia Other