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Procedure

Pancreaticoduodenectomy (Whipple resection), partial pancreatectomy Pancreaticoduodenectomy (Whipple resection), toatl pancreatectomy Excisional biopsy (enucleation) Distal pancreatectomy (pancreatic tail) Segmental pancreatectomy (pancreatic body) Other Not specified

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Tumor Site A word about pancreactic anatomy

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A word about pancreactic anatomy

Pancreatic head Uncinate process Pancreatic body Pancreatic tail Other Cannot be determined Not specified

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Tumor Size (cm)

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Tumor Focality

Unifocal Multifocal Cannot be determined

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Histologic Type and Grade

G1: Well-differentiated neuroendocrine tumor G2: Well-differentiated neuroendocrine tumor G3: Well-differentiated neuroendocrine tumor Other GX: Well-differentiated neuroendocrine tumor, grade cannot be assessed Not applicable

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Mitotic Rate

<2 mitoses/2 mm2 2 to 20 mitoses/2 mm2 >20 mitoses per 2 mm2 Cannot be determined Not applicable

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Ki-67 Labeling Index

<3% 3% to 20% >20% Cannot be determined Not applicable

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+ Tumor Necrosis

Not identified Present Not applicable Cannot be determined

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Tumor Extension (select all that apply)

No evidence of primary tumor Tumor is limited to the pancreas Tumor invades the common bile duct Tumor invades the duodenum Tumor invades adjacent organs Tumor invades the wall of large vessels Cannot be assessed

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Margins

All margins are uninvolved by invasive carcinoma and high-grade intraepithelial neoplasia At least one margin involved by invasive carcinoma

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Lymphovascular Invasion

Not identified Present Cannot be determined

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Perineural Invasion

Not identified Present Cannot be determined

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Regional Lymph Nodes

Check here if any lymph nodes submitted?

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Pathologic Staging (pTNM)

TNM Descriptors (select all that apply)

Not applicable m r y

pT

pTX: Tumor cannot be assessed pT1: Tumor limited to the pancreas, <2 cm pT2: Tumor limited to the pancreas, 2-4 cm pT3: Tumor limited to the pancreas, >4 cm; or tumor invading the duodenum or common bile duct pT4: Tumor invading adjacent organs

pN

pNX: Regional lymph nodes cannot be assessed pN0: No regional lymph node involvement pN1: Regional lymph node involvement

pM

pMx: Not applicable pM1a: Metastasis confined to liver pM1b: Metastasis in at least one extrahepatic site pM1c: Both hepatic and extrahepatic metastases

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+ Additional Pathologic Findings

None identified Atrophy Chronic inflammation Acute pancreatitis Adenomatosis (multiple neuroendocrine tumors, each less than 5 mm in greatest dimension) Other

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+ Clinical History

Von Hippel-Lindau disease Multiple endocrine neoplasia type 1 Familial pancreatic cancer syndrome Hypoglycemic syndrome Necrolytic migratory erythema Watery diarrhea Hypergastrinemia Zollinger-Ellison syndrome Other Not specified