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Tumor Size (cm)
Other Tissue/Organ Involvement
Pathologic Staging (pTNM)
Why no pN
TNM Descriptors (select all that apply)
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+ FIGO Stage (2015 FIGO Cancer Report)
+ Ancillary Studies
Immunohistochemistry in trophoblastic tumors
Immunohistochemistry in the Distinction of, Placental Site Nodule, Placental Site Trophoblastic Tumor,
Epithelioid Trophoblastic Tumor, and Choriocarcinoma by Kurman and Shih has dissected the subpopulations
of trophoblast that give rise to trophoblast tumors and tumor-like lesions.
It is proposed that exaggerated placental site and placental site trophoblastic
tumor arise from implantation site intermediate trophoblast, whereas placental site
nodule and epithelioid trophoblastic tumor arise from chorionic-type intermediate trophoblast.
A panel of immunohistochemical stains (see below) is recommended to distinguish these entities.