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Procedure

Partial urethrectomy Total urethrectomy Urethrectomy with cystectomy Urethrectomy with cystoprostatectomy Urethrectomy with penectomy Anterior exenteration Other Not specified

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+ Tumor Site (select all that apply)

Penile urethra Bulbomembranous urethra Prostatic urethra Anterior urethra Posterior urethra Urethra, not otherwise specified

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+ Tumor Size (cm)

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Histologic Type

Papillary urothelial carcinoma, noninvasive Papillary urothelial carcinoma, invasive Urothelial carcinoma in situ Urothelial carcinoma, invasive Urothelial carcinoma, nested (including large nested) variant Urothelial carcinoma, microcystic variant Urothelial carcinoma, micropapillary variant Urothelial carcinoma, lymphoepithelioma-like variant Urothelial carcinoma, plasmacytoid / signet ring / diffuse variant Urothelial carcinoma, sarcomatoid variant Urothelial carcinoma, giant cell variant Urothelial carcinoma, poorly differentiated variant Urothelial carcinoma, lipid-rich variant Urothelial carcinoma, clear cell variant Urothelial carcinoma with squamous differentiation Urothelial carcinoma with glandular differentiation Urothelial carcinoma with trophoblastic differentiation Urothelial carcinoma with Mϋllerian differentiation Squamous cell carcinoma Verrucous (Squamous cell) carcinoma Squamous cell carcinoma in situ only Adenocarcinoma Adenocarcinoma, enteric Adenocarcinoma, mucinous Adenocarcinoma, mixed Adenocarcinoma in situ only Clear cell carcinoma Endometrioid carcinoma Small cell neuroendocrine carcinoma Large cell neuroendocrine carcinoma Well-differentiated neuroendocrine carcinoma Other histologic type

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+ Associated Epithelial Lesions

None identified Condyloma Squamous dysplasia (low, intermediate, high grade) Urothelial papilloma Urothelial papilloma, inverted type Papillary urothelial neoplasm, low malignant potential (PUNLMP) Urothelial proliferation of uncertain malignant potential Urothelial dysplasia Cannot be determined

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Tumor Extension

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Margins - Invasive

Uninvolved by invasive carcinoma and carcinoma in situ/ noninvasive urothelial carcinoma Uninvolved by invasive carcinoma; dysplasia is present Involved by invasive carcinoma

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+ Lymphovascular Invasion

Not identified Present Cannot be determined

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Regional Lymph Nodes

Check here if any lymph nodes submitted?

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Pathologic Staging (pTNM)

TNM Descriptors (select all that apply)

Not applicable m r y

pT

pTX: Primary tumor cannot be assessed pT0: No evidence of primary tumor pTa: Non-invasive papillary carcinoma pTis: Carcinoma in situ pT1: Tumor invades subepithelial connective tissue pT2: Tumor invades any of the following: corpus spongiosum, periurethral muscle pT3: Tumor invades any of the following: corpus cavernosum, anterior vagina pT4: Tumor invades other adjacent organs (eg, invasion of the bladder wall pTa: Non-invasive papillary carcinoma pTis: Carcinoma in situ involving the prostatic urethra or periurethral or prostatic ducts without stromal invasion pT1: Tumor invades urethral subepithelial connective tissue immediately underlying the urothelium pT2: Tumor invades the prostatic stroma surrounding ducts either by direct extension from the urothelial surface or by invasion from prostatic ducts pT3: Tumor invades the periprostatic fat pT4: Tumor invades other adjacent organs (eg, extraprostatic invasion of the bladder wall, rectal wall)

pN

pNX: Regional lymph nodes cannot be assessed pN0: No regional lymph node metastasis pN1: Single regional lymph node metastasis in the inguinal region or true pelvis (perivesical, obturator, internal [hypogastric] and external iliac), or presacral lymph node pN2: Multiple regional lymph node metastasis in the inguinal region or true pelvis (perivesical, hypogastric, obturator, internal and external iliac, or presacral lymph node)

pM

pMx: Not applicable pM1: Distant metastasis

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+ Additional Pathologic Findings

Keratinizing squamous metaplasia Inflammation/regenerative changes Therapy-related changes Urethritis cystica et glandularis Intestinal metaplasia Other