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Procedure

Local resection Enucleation Limited exenteration Complete exenteration Other Not specified

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Specimen Laterality

Right Left Not specified

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Tumor Site - macroscopic examination/transillumination (select all that apply)

Superotemporal quadrant of globe Superonasal quadrant of globe Inferotemporal quadrant of globe Inferonasal quadrant of globe Anterior chamber Between x and y o'clock Other

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Tumor Size After Sectioning - Greatest basal diameter (mm)

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Tumor Size After Sectioning - Greatest thickness (mm)

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Tumor Site After Sectioning

Cannot be determined Superonasal Inferonasal Superotemporal Inferotemporal

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Tumor Involvement of Other Ocular Structures

Sclera Vortex vein(s) Optic nerve head Vitreous Choroid Ciliary body Iris Lens Anterior chamber Extrascleral extension (anterior) Extrascleral extension (posterior) Angle/Schlemm’s canal Optic nerve Retina Cornea Other Cannot be assessed

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Growth Pattern

Cannot be determined Solid mass Dome shape Mushroom shape Diffuse (ciliary body ring) Diffuse (flat)

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Histologic Type

Spindle cell melanoma (>90% spindle cells) Mixed cell melanoma (>10% epithelioid cells and <90% spindle cells) Epithelioid cell melanoma (>90% epithelioid cells)

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Scleral Involvement

None Intrascleral Extrascleral (≤5 mm largest diameter) Extrascleral (>5 mm largest diameter) Cannot be determined

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Margins

Cannot be assessed No melanoma at margins Extrascleral extension (for enucleation specimens) Other margin(s) involved

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Regional Lymph Nodes

Check here if any lymph nodes submitted?

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Pathologic Staging (pTNM)

Click for information on how to choose the pT group

TNM Descriptors (select all that apply)

Not applicable m r y

pT

pTX: Primary tumor cannot be assessed pT0: No evidence of primary tumor pT1a: Tumor limited to the iris not more than 3 clock hours in size pT1b: Tumor limited to the iris more than 3 clock hours in size pT1c: Tumor limited to the iris with secondary glaucoma pT2a: Tumor confluent with or extending into the ciliary body, without secondary glaucoma pT2b: Tumor confluent with or extending into the ciliary body and choroid, without secondary glaucoma pT2c: Tumor confluent with or extending into the ciliary body, choroid, or both, with secondary glaucoma pT3: Tumor confluent with or extending into the ciliary body, choroid, or both, with scleral extension pT4a: Tumor with extrascleral extension ≤5 mm in largest diameter pT4b: Tumor with extrascleral extension >5 mm in largest diameter pTX: Primary tumor cannot be assessed pT0: No evidence of primary tumor pT1a: Tumor size category 1 without ciliary body involvement and extraocular extension pT1b: Tumor size category 1 with ciliary body involvement pT1c: Tumor size category 1 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter pT1d: Tumor size category 1 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter pT2a: Tumor size category 2 without ciliary body involvement and extraocular extension pT2b: Tumor size category 2 with ciliary body involvement pT2c: Tumor size category 2 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter pT2d: Tumor size category 2 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter pT3a: Tumor size category 3 without ciliary body involvement and extraocular extension pT3b: Tumor size category 3 with ciliary body involvement pT3c: Tumor size category 3 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter pT3d: Tumor size category 3 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter pT4a: Tumor size category 4 without ciliary body involvement and extraocular extension pT4b: Tumor size category 4 with ciliary body involvement pT4c: Tumor size category 4 without ciliary body involvement but with extraocular extension ≤5 mm in largest diameter pT4d: Tumor size category 4 with ciliary body involvement and extraocular extension ≤5 mm in largest diameter pT4e: Any tumor size category with extraocular extension >5 mm in largest diameter

pN

pNX: Regional lymph nodes cannot be assessed pN0: No regional lymph node metastasis pN1: Regional lymph node metastasis or discrete tumor deposits in the orbit pN1a: Metastasis in one or more regional lymph node(s) pN1b: No regional lymph nodes are positive, but there are discrete tumor deposits in the orbit that are not contiguous to the eye. (choroidal and ciliary body)

pM

pMx: Not applicable pM1: Distant metastasis pM1a: Largest diameter of the largest metastasis ≤3 cm pM1b: Largest diameter of the largest metastasis 3.1-8.0 cm pM1c: Largest diameter of the largest metastasis ≥8.1 cm

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+ Additional Pathologic Findings (select all that apply)

Mitotic rate Extravascular matrix pattern Vascular invasion (tumor vessels or other vessels) Degree of pigmentation Inflammatory cells/tumor infiltrating lymphocytes and macrophages Drusen Retinal detachment Invasion of Bruch’s membrane Nevus Hemorrhage Neovascularization Other